相同組換えによってDNAが修復される際には、最終段階でDNA合成が起こる。今回、DNAヘリカーゼPif1がこの反応で果たす役割が、2つの論文によって明らかになった。Pif1がない場合、DNA鎖切断により誘発される複製（break-induced replication；BIR）の初期段階は正常に ...
When chromosomes experience double-strand breaks resulting from oxidation, ionizing radiation, replication errors and certain metabolic products in cells, they utilize their genetically similar ...
Proteins PIF1 and PCNA gather at sites of DNA damage in SETX-deficient cells, indicating activation of the BIR repair system. LA JOLLA, CA—The DNA inside our cells is constantly being damaged, and one ...
The DNA inside our cells is constantly being damaged, and one of the worst kinds of damage is a double-strand break-when both sides of the DNA helix are cut at once. Healthy cells can normally fix ...
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