Codon usage bias (CUB)—the nonuniform usage of synonymous codons—is a feature of all genomes and varies across species. Differences in CUB imply differences in the underlying microevolutionary ...
Highly expressed genes are encoded by codons that correspond to abundant tRNAs, a phenomenon thought to ensure high expression levels. An alternative interpretation is that highly expressed genes are ...
Department of Biology, Faculty of Arts and Sciences, Recep Tayyip Erdoğan University, Rize, Türkiye Honeybee viruses (HVs) are some of the most significant pathogens affecting these insects and are ...
Bluetongue virus (BTV) causes a vector-borne viral disease [bluetongue (BT)], is an economically important virus of ruminants that belongs to the genus Orbivirus of the Reoviridae family, and has a ...
Coronaviruses (CoVs) are single-stranded RNA viruses which contain the largest RNA genomes, and severe acute respiratory syndrome coronavirus (SARS-CoV), a newly found group 2 CoV, emerged as ...
Codon usage biases are found in all eukaryotic and prokaryotic genomes, and preferred codons are more frequently used in highly expressed genes. The effects of codon usage on gene expression were ...
Genes are made up of DNA, which contains all the information and instruction needed to build an organism. This information is stored as a genetic code consisting of four bases: adenine (A), cytosine ...
The cell cycle is a temporal program that regulates DNA synthesis and cell division. When we compared the codon usage of cell cycle‐regulated genes with that of other genes, we discovered that there ...
Codon usage bias, the preference for certain synonymous codons, is found in all genomes. Although synonymous mutations were previously thought to be silent, a large body of evidence has demonstrated ...
What does this project do? This project is a tool that analyzes the codon usage in a DNA sequence and suggests an optimized version based on the preferred codon usage of a target organism (e.g., E.