Pulmonology Advisor

CT-Based Severity Scoring System, Elastic PRM, Predicts COPD Advancement

Elastic parametric response mapping (ePRM), a CT-based severity scoring system for regional lung volumes, can monitor COPD progression.
eLife

A proteome-wide biochemical screen defines binding determinants of the core autophagy ...

Human MAP1LC3B (LC3B) binds proteins involved in autophagy and other cellular processes using a degenerate four-residue short linear motif known as the LC3-interacting region (LIR). Biochemical and ...
Open Heart

Enhanced cardiovascular disease risk prediction using integrated machine learning models: a ...

Objective Cardiovascular diseases (CVD) remain the leading cause of mortality globally, necessitating early risk ...
AHA/ASA Journals

HEV-Targeted Antibody-Drug Conjugate Promotes Long-Term Cardiac Allograft Acceptance

BACKGROUND: The entrance of naive T cells into lymph nodes (LNs) is a crucial step for induction of heart transplant acceptance under costimulatory blockade. Specialized blood vessels within the LN ...
eLife

Cytoplasmatic polyadenylation of mRNA by TENT5A is critical for enamel mineralization

This study reports an important and novel finding that TENT5A, an enzyme involved in fine-tuning poly(A) tail length on selected mRNAs, is required for proper enamel mineralization in mice. The ...